BDBM50074991 (E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-methyl-benzothiazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-amide::CHEMBL113222

SMILES CN(C(=O)CNC(=O)\C=C\C=C)c1ccc(Cl)c(COc2cccc3sc(C)nc23)c1Cl

InChI Key InChIKey=RGYRXPGQPRYXCH-WEVVVXLNSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074991   

TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074991((E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-me...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074991((E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-me...)
Affinity DataIC50:  26nMAssay Description:Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074991((E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-me...)
Affinity DataEC50:  260nMAssay Description:Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed