BDBM50075058 ((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(3-methoxy-phenyl)-thiazol-2-yl]-tetrahydro-furan-2-ylmethyl ester::CHEMBL125075

SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1cccc(OC)c1

InChI Key InChIKey=SKMGGGPZQRRMTG-DPLAEZHRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075058   

TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  50nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  15nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed