BDBM50076851 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-thiophen-2-yl-thiazole::CHEMBL16689

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc(nc1-c1ccc(F)cc1)-c1cccs1

InChI Key InChIKey=ISMZMNIRFHOTII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076851   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076851(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076851(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human cyclooxygenase-1 (hCOX-1) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed