BDBM50077740 5-[(E)-3-(3-Nitro-phenyl)-acryloylamino]-1H-[1,2,4]triazole-3-carboxylic acid {(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-2-cyclohexyl-ethyl}-amide::CHEMBL286648
SMILES NC([NH-])=[NH+]CCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1nnc(NC(=O)C=Cc2cccc(c2)[N+]([O-])=O)[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key InChIKey=JFFOJDXZUTVITE-KCHLEUMXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50077740
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to Thrombin receptor 1 (PAR-1) on membranes from CHRF cellsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombinMore data for this Ligand-Target Pair