BDBM50078820 6,7-Dihydroxy-4-methyl-chromen-2-one::6,7-dihydroxy-4-methyl-2H-chromen-2-one::CHEMBL313244

SMILES Cc1cc(=O)oc2cc(O)c(O)cc12

InChI Key InChIKey=KVOJTUXGYQVLAJ-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50078820   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50078820(6,7-Dihydroxy-4-methyl-chromen-2-one | 6,7-dihydro...)
Affinity DataKi:  1.19E+3nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50078820(6,7-Dihydroxy-4-methyl-chromen-2-one | 6,7-dihydro...)
Affinity DataIC50:  2.46E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50078820(6,7-Dihydroxy-4-methyl-chromen-2-one | 6,7-dihydro...)
Affinity DataIC50:  6.28E+3nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSorbitol dehydrogenase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50078820(6,7-Dihydroxy-4-methyl-chromen-2-one | 6,7-dihydro...)
Affinity DataIC50:  2.12E+5nMAssay Description:Inhibition sorbitol dehydrogenase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50078820(6,7-Dihydroxy-4-methyl-chromen-2-one | 6,7-dihydro...)
Affinity DataKd:  1.50E+6nMAssay Description:Dissociation constant when binding to FK506 binding protein (FKBP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50078820(6,7-Dihydroxy-4-methyl-chromen-2-one | 6,7-dihydro...)
Affinity DataIC50:  6.44E+4nMAssay Description:Inhibition human recombinant aldose reductase 1 by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed