BDBM50081701 3-[2-(dimethylamino)ethyl]-1H-indol-4-ol::4-hydroxy-N,N-dimethyltryptamine::CHEMBL65547::N,N-dimethyl-4-hydroxytryptamine::Psilocin::US11427604, Compound (I-45)::US11453689, Compound Psilocin::US11591353, Compound I-45::US11597738, Example 3::US11642336, Compound Psilocin::US20240051978, Compound Psilocin

SMILES CN(C)CCc1c[nH]c2cccc(O)c12

InChI Key InChIKey=SPCIYGNTAMCTRO-UHFFFAOYSA-N

Data  24 KI  11 IC50  15 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50081701   

Target5-hydroxytryptamine receptor 2A(Mus musculus (Mouse))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081701(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Mus musculus (Mouse))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081701(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Affinity DataEC50:  9.90nMAssay Description:Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081701(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081701(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed