BDBM50081743 1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-benzyl)-piperidine::CHEMBL318424

SMILES Cc1ccc(CC2CCN(CCC#Cc3cnc[nH]3)CC2)cc1

InChI Key InChIKey=DIZCVAGMXVUHPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081743   

TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081743(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Affinity DataIC50:  3.80E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081743(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Affinity DataIC50:  20nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081743(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Affinity DataIC50:  1.60E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed