BDBM50081746 1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piperidine::CHEMBL96744

SMILES C(CN1CCC(CC1)c1ccccc1)C#Cc1cnc[nH]1

InChI Key InChIKey=ZALGNZKPJDVGDG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081746   

TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081746(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081746(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  810nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081746(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed