BDBM50081748 4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piperidine::CHEMBL93873

SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cnc[nH]1

InChI Key InChIKey=CXSBVUAWHYXWQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081748   

TargetGlutamate receptor ionotropic, NMDA 3A(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081748(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50:  5.30E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081748(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50:  37nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50081748(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50:  7.00E+4nMAssay Description:Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed