BDBM50082322 1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-3-phenoxy-propan-2-ol; hydrochloride::CHEMBL543622

SMILES OC(COc1ccccc1)CN1CCC(CC1)c1ccc(Cc2ccc(F)cc2)cc1

InChI Key InChIKey=VWQGDNWLMBJUHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082322   

TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082322(1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...)
Affinity DataIC50:  360nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082322(1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed