BDBM50089398 CHEMBL3577981

SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O

InChI Key InChIKey=MTKQTEXYJKPBQD-GNDHHEKASA-N

Data  2 KI  5 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50089398   

TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataKi:  20nMAssay Description:Displacement of MTII from mouse MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataKi:  400nMAssay Description:Displacement of MTII from mouse MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC4R by alphascreen cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataIC50:  70nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Mus musculus (Mouse))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataIC50:  1.23E+4nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 5 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataIC50:  70nMAssay Description:Displacement of [125I]-NDP-MSH from human melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataIC50:  1.70E+4nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 3 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC3R by alphascreen cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by cAMP functional bioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Mus musculus (Mouse))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataEC50: >1.00E+8nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells by cAMP functional bioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089398(CHEMBL3577981)
Affinity DataIC50:  9.00E+3nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 1 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed