BDBM50091149 (4-Chloro-benzyl)-[3-(2-chloro-phenothiazin-10-yl)-propyl]-dimethyl-ammonium (OFK002)::CHEMBL105769

SMILES C[N+](C)(CCCN1c2ccccc2Sc2ccc(Cl)cc12)Cc1ccc(Cl)cc1

InChI Key InChIKey=YFVOLUIACKGBQW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091149   

TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50091149((4-Chloro-benzyl)-[3-(2-chloro-phenothiazin-10-yl)...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50091149((4-Chloro-benzyl)-[3-(2-chloro-phenothiazin-10-yl)...)
Affinity DataKi:  2.20E+6nMAssay Description:Inhibitory activity against Human Erythrocyte glutathione reductase (GR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50091149((4-Chloro-benzyl)-[3-(2-chloro-phenothiazin-10-yl)...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed