BDBM50091293 CHEMBL3582201

SMILES N#Cc1cc2c(cn1)[nH]c1ncc(cc21)-c1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=PPYHOOZGDDPLKM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091293   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091293(CHEMBL3582201)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091293(CHEMBL3582201)
Affinity DataEC50:  53nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091293(CHEMBL3582201)
Affinity DataIC50:  333nMAssay Description:Inhibition of human acetylcholine esterase by horseradish peroxidase-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed