BDBM50093195 CHEMBL80502::Derivative of piperazine-1-carboxylic acid 5-(piperazine-1-carbonyloxy)-cyclooctyl ester

SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#7]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#8]-[#6@@H]-2-[#6]-[#6]-[#6]-[#6@@H](-[#6]-[#6]-[#6]-2)-[#8]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6]-[#6]-[#6]-[#6]-n2ccnc2)cc1

InChI Key InChIKey=IPOXMAWFPOIAPU-RNPORBBMSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093195   

TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093195(CHEMBL80502 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  1.00E+3nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093195(CHEMBL80502 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  1.44E+5nMAssay Description:Compound was evaluated for its inhibitory potency against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093195(CHEMBL80502 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093195(CHEMBL80502 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed