BDBM50096109 2-(3-Aminomethyl-phenyl)-5-methyl-2H-pyrazole-3-carboxylic acid (2'-methanesulfonyl-biphenyl-4-yl)-amide::CHEMBL156775

SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(C)(=O)=O)n(n1)-c1cccc(CN)c1

InChI Key InChIKey=WJIPVTTXLNWLTQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096109   

TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096109(2-(3-Aminomethyl-phenyl)-5-methyl-2H-pyrazole-3-ca...)
Affinity DataKi:  220nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096109(2-(3-Aminomethyl-phenyl)-5-methyl-2H-pyrazole-3-ca...)
Affinity DataKi:  890nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096109(2-(3-Aminomethyl-phenyl)-5-methyl-2H-pyrazole-3-ca...)
Affinity DataKi:  2.10E+4nMAssay Description:In vitro activity against human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed