BDBM50096739 (R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-benzo[cd]pyren-2-one::CHEMBL124419

SMILES CN1CCc2ccc3oc(=O)c4cccc5C[C@@H]1c2c3c45

InChI Key InChIKey=UCVKKWQVIIHPLH-CYBMUJFWSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50096739   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  265nMAssay Description:In vitro binding affinity of the compound towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]5-HT from rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  1.48E+3nMAssay Description:In vitro binding affinity of the compound towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  2.03E+3nMAssay Description:In vitro binding affinity of the compound towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in rat hippocampus membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed