BDBM50097100 2-Phenyl-quinoline-4-carboxylic acid::2-phenylquinoline-4-carboxylic acid::CHEMBL348000::Cinchophen
SMILES OC(=O)c1cc(nc2ccccc12)-c1ccccc1
InChI Key InChIKey=YTRMTPPVNRALON-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50097100
Affinity DataIC50: >1.00E+5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Aminoacylation activity against human prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.95E+5nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibition of DHODH (unknown origin) expressed in Escherichia coli Rosetta2(DE3) assessed as reduction of DCIP using dihydroorotate as substrate prei...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKd: 1.27E+5nMAssay Description:Binding affinity to human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) after 15 mins by SPR inhibition in solution assayMore data for this Ligand-Target Pair
Affinity DataIC50: >8.14E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.96E+5nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair