BDBM50097373 4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-carbonitrile::4-Imidazol-1-ylmethyl-9-oxo-9H-xanthene-1-carbonitrile::CHEMBL421149

SMILES O=c1c2ccccc2oc2c(Cn3ccnc3)ccc(C#N)c12

InChI Key InChIKey=QNFMJFCMHIQSTD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097373   

TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097373(4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097373(4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human aromatase using [1beta,2beta3H]-]testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097373(4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50097373(4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human placental aromatase in presence of [1beta,2beta-3H] testosterone by Thompson and Siiteri methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed