BDBM50097820 4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-dienyl)-but-3-en-1-ynyl]-benzoic acid::CHEMBL350485

SMILES Cc1ccc(cc1)C1=CCC(C)(C)C=C1\C=C\C#Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=UACAJGJFJAQPLY-FNORWQNLSA-N

Data  3 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097820   

TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097820(4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-die...)
Affinity DataIC50:  225nMAssay Description:Antagonist activity of TTNPB (10 nM) function at retinoic acid receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097820(4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-die...)
Affinity DataKd:  4nMAssay Description:Binding affinity towards retinoic acid receptor gamma was determined using [3H]-ATRA (5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097820(4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-die...)
Affinity DataKd:  35nMAssay Description:Binding affinity towards retinoic acid receptor alpha was determined using [3H]-ATRA (5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097820(4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-die...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity of TTNPB (10 nM) function at retinoic acid receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097820(4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-die...)
Affinity DataKd:  129nMAssay Description:Binding affinity towards retinoic acid receptor gamma was determined using [3H]-ATRA (5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50097820(4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-die...)
Affinity DataIC50:  53nMAssay Description:Antagonist activity of TTNPB (10 nM) function at retinoic acid receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed