BDBM50099398 5-Bromo-1H-indazole::CHEMBL16425::cid_761929

SMILES Brc1ccc2[nH]ncc2c1

InChI Key InChIKey=STVHMYNPQCLUNJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50099398   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50099398(5-Bromo-1H-indazole | CHEMBL16425 | cid_761929)
Affinity DataIC50:  1.63E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50099398(5-Bromo-1H-indazole | CHEMBL16425 | cid_761929)
Affinity DataIC50:  7.50E+4nMAssay Description:In vitro inhibitory concentration against rat cerebellar neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50099398(5-Bromo-1H-indazole | CHEMBL16425 | cid_761929)
Affinity DataIC50:  4.10E+5nMAssay Description:Negative allosteric modulation activity at CK2alpha (unknown origin) assessed as inhibition of CK2alphaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50099398(5-Bromo-1H-indazole | CHEMBL16425 | cid_761929)
Affinity DataIC50:  3.70E+4nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Uned

Curated by ChEMBL
LigandPNGBDBM50099398(5-Bromo-1H-indazole | CHEMBL16425 | cid_761929)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of NOS1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50099398(5-Bromo-1H-indazole | CHEMBL16425 | cid_761929)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed