BDBM50101853 (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid::(13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid::11alpha,15alpha-dihydroxy-9-oxo-13-trans-prostenoic acid::ALPROSTADIL::CHEMBL495::PGE-1::PGE1::prostaglandin E1
SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
InChI Key InChIKey=GMVPRGQOIOIIMI-DWKJAMRDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 37 hits for monomerid = 50101853
Affinity DataEC50: 1.80nMAssay Description:Effective concentration which increases intracellular c-AMP production in human Prostanoid IP receptorMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Rat)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at Nurr1 in rat N27-A cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Rat)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at Nurr1 in rat N27-A cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Mouse)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at Nurr1 in mouse MN9D cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Mouse)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at Nurr1 in mouse MN9D cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [3H]iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 2B1(Rat)
Tohoku University School of Medicine
Curated by ChEMBL
Tohoku University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:TP_TRANSPORTER: inhibition of PGD2 uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Affinity for mouse Prostanoid EP4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity towards mouse Prostanoid EP4 receptor in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Affinity for mouse Prostanoid EP4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Affinity for mouse Prostanoid EP3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Evaluated for its competitive binding affinity towards mouse Prostanoid EP3 receptor in CHO cells expressing prostanoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Affinity for mouse Prostanoid EP3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Evaluated for its competitive binding affinity towards mouse Prostanoid EP1 receptor in CHO cells expressing prostanoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Affinity for mouse Prostanoid EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Affinity for mouse Prostanoid EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Evaluated for its competitive binding affinity towards mouse Prostanoid EP2 receptor in CHO cells expressing prostanoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Affinity for mouse Prostanoid EP2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Affinity for mouse Prostanoid EP2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity towards mouse Prostanoid EP1 receptor in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Affinity for human Prostanoid IP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Evaluated for its competitive binding affinity towards human Prostanoid IP receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Binding affinity towards human Prostanoid IP receptor in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for human Prostanoid IP receptor expressed in CHO cellsMore data for this Ligand-Target Pair