BDBM50103072 1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole::CHEMBL56900::Lerisetron
SMILES C(c1ccccc1)n1c(nc2ccccc12)N1CCNCC1
InChI Key InChIKey=PWWDCRQZITYKDV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50103072
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe
Curated by ChEMBL
The University Of Louisiana At Monroe
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:In vitro by displacement of [3H]raclopride from Dopamine receptor D2 on rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:In vitro by displacement of [3H]GR-113808 from 5-hydroxytryptamine 4 receptor on guinea pig striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:In vitro by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor on rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity was evaluated in vitro by displacement of [3H]ketanserin from 5-hydroxytryptamine 2A receptor on rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor in striatum membranes of guinea-pig brain was evaluatedMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity towards Dopamine receptor D2 in rat was evaluatedMore data for this Ligand-Target Pair