BDBM50103140 CHEMBL3394929

SMILES Cc1cn(cn1)-c1ccc2C(=O)N(Cc3[nH]c4ccccc4c3Cl)CCn2c1=O

InChI Key InChIKey=SGTHQYCRONMHFS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103140   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50103140(CHEMBL3394929)Copy SMILESCopy InChI

Affinity DataIC50:  207nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in CHO cells overexpressing human wild type APP assessed as reduction of amyloid beta 42 lev...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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