BDBM50103450 CHEMBL3398249

SMILES FC(F)(F)c1cc(NCc2ccccc2)c2SSSSSc2c1

InChI Key InChIKey=NWFUAWKNPDQRRG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103450   

TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103450(CHEMBL3398249)
Affinity DataKi:  175nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103450(CHEMBL3398249)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of STEP (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate in presence of 1 mM GSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103450(CHEMBL3398249)
Affinity DataIC50:  78nMAssay Description:Inhibition of STEP (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate in absence of GSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed