BDBM50103985 CHEMBL320442::N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(thiophen-3-ylmethylsulfanyl)-butyramide

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C(CCSCc1ccsc1)C(=O)NO

InChI Key InChIKey=NQHPVFGLBXTGFR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50103985   

TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103985(CHEMBL320442 | N-Hydroxy-2-[isobutyl-(4-methoxy-be...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103985(CHEMBL320442 | N-Hydroxy-2-[isobutyl-(4-methoxy-be...)
Affinity DataIC50:  188nMAssay Description:In vitro inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103985(CHEMBL320442 | N-Hydroxy-2-[isobutyl-(4-methoxy-be...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103985(CHEMBL320442 | N-Hydroxy-2-[isobutyl-(4-methoxy-be...)
Affinity DataIC50:  5.10nMAssay Description:In vitro inhibition of human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103985(CHEMBL320442 | N-Hydroxy-2-[isobutyl-(4-methoxy-be...)
Affinity DataIC50:  5.40nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed