BDBM50105241 6,7-Dichloro-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo[e][1,2]thiazine-3-carboxylic acid (1-benzyl-2-oxo-ethyl)-amide::CHEMBL118688

SMILES CN1C(Cc2cc(Cl)c(Cl)cc2S1(=O)=O)C(=O)N[C@@H](Cc1ccccc1)C=O

InChI Key InChIKey=WGAWTZRUUNHJGZ-MBIQTGHCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105241   

TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105241(6,7-Dichloro-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity towards human calpain IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105241(6,7-Dichloro-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity towards human calpain IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105241(6,7-Dichloro-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory concentration against MOLT-4 cells (human T-cell leukemia cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed