BDBM50105450 2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL92899

SMILES ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccccc3)cc2)CCCN1CC#C

InChI Key InChIKey=BHBGOKVZFAQJAD-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50105450   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: <0.100nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: <0.100nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed