BDBM50105462 CHEMBL81880::N,N,N',N'-Tetramethyl-acridine-3,6-diamine

SMILES CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C

InChI Key InChIKey=DPKHZNPWBDQZCN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105462   

TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50105462(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50105462(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50105462(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Affinity DataIC50:  600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50105462(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50105462(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed