BDBM50105675 (E)-3-[4-(4-Chloro-benzenesulfonylamino)-phenyl]-N-hydroxy-acrylamide::3-(4-(4-chlorophenylsulfonamido)phenyl)-N-hydroxyacrylamide::CHEMBL318642::US8796330, 88
SMILES ONC(=O)\C=C\c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1
InChI Key InChIKey=XYDHOUZMEAEBTG-XCVCLJGOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50105675
Affinity DataIC50: 75nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of Homo sapiens (human) HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair