BDBM50105677 (E)-N-Hydroxy-3-[4-(toluene-4-sulfonylamino)-phenyl]-acrylamide::CHEMBL317570::N-Hydroxy-3-[4-(toluene-4-sulfonylamino)-phenyl]-acrylamide::N-hydroxy-3-(4-(4-methylphenylsulfonamido)phenyl)acrylamide::US8796330, 108
SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C\C(=O)NO)cc1
InChI Key InChIKey=PAOPWNUFHBHBRD-IZZDOVSWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50105677
Affinity DataIC50: 300nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of Homo sapiens (human) HDAC8More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of acetylation of histone-4 in human T-24 cancer cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against human Histone deacetylase 1More data for this Ligand-Target Pair