BDBM50106137 CHEMBL100280::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-morpholin-4-ylmethyl-benzamide

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCOCC2)cccc1C(=O)NO

InChI Key InChIKey=WGMQZHYPIKBUML-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106137   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106137(CHEMBL100280 | N-Hydroxy-2-[(4-methoxy-benzenesulf...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106137(CHEMBL100280 | N-Hydroxy-2-[(4-methoxy-benzenesulf...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106137(CHEMBL100280 | N-Hydroxy-2-[(4-methoxy-benzenesulf...)
Affinity DataIC50:  174nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106137(CHEMBL100280 | N-Hydroxy-2-[(4-methoxy-benzenesulf...)
Affinity DataIC50:  608nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed