BDBM50106432 (3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinolin-1-yl)-methanone::CHEMBL130994

SMILES Oc1ccc(cc1O)C(=O)c1[nH]c(=O)cc2cc(O)c(O)cc12

InChI Key InChIKey=JDHSEPKENKFHQF-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106432   

TargetInsulin-like growth factor-binding protein 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  6.20nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 2(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  17nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  21nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against Insulin-like growth factor binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  34nMAssay Description:The compound was tested for binding affinity against insulin-like growth factor binding protein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  85nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed