BDBM50107276 CHEMBL3600696

SMILES CNC(=O)c1ccc(cn1)-c1ccc2nc(N)sc2c1

InChI Key InChIKey=HLYCMIUSQBLQAY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107276   

TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50107276(CHEMBL3600696)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-kinase alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50107276(CHEMBL3600696)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length recombinant PI4K3alpha using D-myo-phosphatidylinositol substrate and ATP incubated for 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50107276(CHEMBL3600696)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of N-terminal GST-tagged human full length recombinant PI4K3beta expressed in Sf9 cells using D-myo-phosphatidylinositol substrate and ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50107276(CHEMBL3600696)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed