BDBM50107768 4'-Chloro-6-methyl-biphenyl-2-carboxylic acid [2-(methanesulfonylamino-methyl)-indan-5-yl]-amide::CHEMBL142616

SMILES Cc1cccc(C(=O)Nc2ccc3CC(CNS(C)(=O)=O)Cc3c2)c1-c1ccc(Cl)cc1

InChI Key InChIKey=WGCXUGFPWKBWOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107768   

TargetApolipoprotein B-100(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107768(4'-Chloro-6-methyl-biphenyl-2-carboxylic acid [2-(...)
Affinity DataIC50:  16nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107768(4'-Chloro-6-methyl-biphenyl-2-carboxylic acid [2-(...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed