BDBM50107776 4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-benzylamino-indan-5-yl)-amide::CHEMBL142519

SMILES FC(F)(F)c1ccc(cc1)-c1ccccc1C(=O)Nc1ccc2CC(Cc2c1)NCc1ccccc1

InChI Key InChIKey=XVGZFRXMWRNZPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107776   

TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107776(4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-b...)
Affinity DataIC50:  4.80E+3nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApolipoprotein B-100(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107776(4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-b...)
Affinity DataIC50:  340nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed