BDBM50107795 4'-Trifluoromethyl-biphenyl-2-carboxylic acid [2-(3,3-dimethyl-ureido)-indan-5-yl]-amide::CHEMBL143647

SMILES CN(C)C(=O)NC1Cc2ccc(NC(=O)c3ccccc3-c3ccc(cc3)C(F)(F)F)cc2C1

InChI Key InChIKey=TZNSZZMLARSGAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107795   

TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107795(4'-Trifluoromethyl-biphenyl-2-carboxylic acid [2-(...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApolipoprotein B-100(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107795(4'-Trifluoromethyl-biphenyl-2-carboxylic acid [2-(...)
Affinity DataIC50:  120nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed