BDBM50107806 4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-benzenesulfonylamino-indan-5-yl)-amide::CHEMBL434703

SMILES FC(F)(F)c1ccc(cc1)-c1ccccc1C(=O)Nc1ccc2C[C@@H](Cc2c1)NS(=O)(=O)c1ccccc1

InChI Key InChIKey=SPCXYBUWDJJYRU-DEOSSOPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107806   

TargetApolipoprotein B-100(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107806(4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-b...)
Affinity DataIC50:  42nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107806(4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-b...)
Affinity DataIC50:  650nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed