BDBM50107815 6-Methyl-4'-trifluoromethyl-biphenyl-2-carboxylic acid {2-[(thiophene-2-sulfonylamino)-methyl]-indan-5-yl}-amide::CHEMBL143626

SMILES Cc1cccc(C(=O)Nc2ccc3CC(CNS(=O)(=O)c4cccs4)Cc3c2)c1-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IECYXABIVIGSDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107815   

TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107815(6-Methyl-4'-trifluoromethyl-biphenyl-2-carboxylic ...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApolipoprotein B-100(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107815(6-Methyl-4'-trifluoromethyl-biphenyl-2-carboxylic ...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed