BDBM50107964 6-[(2,5-Dibromo-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL147131

SMILES Cc1c(CNc2cc(Br)ccc2Br)cnc2nc(N)nc(N)c12

InChI Key InChIKey=XHHAAZJLZWLYLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107964   

TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107964(6-[(2,5-Dibromo-phenylamino)-methyl]-5-methyl-pyri...)
Affinity DataIC50:  4.60nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107964(6-[(2,5-Dibromo-phenylamino)-methyl]-5-methyl-pyri...)
Affinity DataIC50:  0.700nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed