BDBM50107965 6-[(2-Fluoro-5-trifluoromethyl-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL358884

SMILES Cc1c(CNc2cc(ccc2F)C(F)(F)F)cnc2nc(N)nc(N)c12

InChI Key InChIKey=WASQWUJCODWDTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107965   

TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107965(6-[(2-Fluoro-5-trifluoromethyl-phenylamino)-methyl...)
Affinity DataIC50:  4.10nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107965(6-[(2-Fluoro-5-trifluoromethyl-phenylamino)-methyl...)
Affinity DataIC50:  0.860nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed