BDBM50107978 6-[(3-Methoxy-biphenyl-4-ylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL147504
SMILES COc1cc(ccc1NCc1cnc2nc(N)nc(N)c2c1C)-c1ccccc1
InChI Key InChIKey=LEJZWCKEJIXXFL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50107978
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair