BDBM50107987 6-[(4-Chloro-2-methoxy-5-methyl-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL345258

SMILES COc1cc(Cl)c(C)cc1NCc1cnc2nc(N)nc(N)c2c1C

InChI Key InChIKey=SLXUBQLLIYKHFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107987   

TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107987(6-[(4-Chloro-2-methoxy-5-methyl-phenylamino)-methy...)
Affinity DataIC50:  0.940nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107987(6-[(4-Chloro-2-methoxy-5-methyl-phenylamino)-methy...)
Affinity DataIC50:  10nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed