BDBM50109637 4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydroxycarbamoyl-piperazine-1-carboxylic acid benzyl ester::CHEMBL173235
SMILES CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1
InChI Key InChIKey=LXKHXLQQHKRMFP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50109637
Affinity DataKi: 5.20nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nippon Organon K.K.
Curated by ChEMBL
Nippon Organon K.K.
Curated by ChEMBL
Affinity DataKi: 7.99nMAssay Description:Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.More data for this Ligand-Target Pair
Affinity DataKi: 14.9nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
Affinity DataKi: 20.1nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Nippon Organon K.K.
Curated by ChEMBL
Nippon Organon K.K.
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...More data for this Ligand-Target Pair