BDBM50111592 6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiophenylidene]-3,3'-dione::CHEMBL45343

SMILES Oc1c2c(cc(Cl)cc2=C)s\c1=c1\sc2cc(Cl)cc(=C)c2c1O

InChI Key InChIKey=ZATNBKBMTXYJPK-ISLYRVAYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111592   

TargetBeta-galactosidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of Beta-galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity against cloned Dihydrofolate reductase (cDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against chymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed