BDBM50111899 5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::5-(2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::CHEMBL54079

SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1ccccc1OCC

InChI Key InChIKey=MXQUEDUMKWBYHI-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50111899   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50: >500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50: >500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  790nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human corpus cavernosum PDE5More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  39.8nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  790nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed