BDBM50111899 5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::5-(2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::CHEMBL54079
SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1ccccc1OCC
InChI Key InChIKey=MXQUEDUMKWBYHI-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50111899
Affinity DataIC50: 27nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human corpus cavernosum PDE5More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B/Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C/Phosphodiesterase(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair