BDBM50112313 2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-ethyl]-benzoyl}-methyl-amino)-pentanedioic acid::CHEMBL57444

SMILES Nc1cc(N)c2c(CCc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)coc2n1

InChI Key InChIKey=JTBQUEMZJXWQEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112313   

TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112313(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-eth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112313(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-eth...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of rocombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed