BDBM50112346 CHEMBL3609325
SMILES [H][C@@]12CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@@]([H])(C1)C(=O)N[C@@H](Cc1ccc3ccccc3c1)C(=O)N[C@@H](Cc1ccc(OCc3cn(nn3)[C@]3([H])CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@@]([H])(C3)C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(=O)N[C@@H](Cc3ccc(OCCCC2)cc3)C(O)=O)cc1)NS(=O)(=O)C1CC1
InChI Key InChIKey=MLQVQPMTZJBGEY-VGEDNRJQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50112346
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of XIAP BIR3 domain (unknown origin)More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of cIAP BIR2-3 domain (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataEC50: 9.40nMAssay Description:Inhibition of XIAP (unknown origin) by caspase-3 rescue assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of PXR (unknown origin) by receptor transactivation assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair