BDBM50114263 ((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-1-cyclohexylmethyl-2-oxo-ethylamino)-acetic acid; compound with ditrifluoro-acetic acid::CHEMBL208140

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2C=CCN2C(=O)[C@@H](CC2CCCCC2)NCC(O)=O)s1

InChI Key InChIKey=BUGKCANFLDYYKD-SJORKVTESA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50114263   

TargetProthrombin(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  3.60nMAssay Description:In vitro Inhibitory concentration against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  328nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  70nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed