BDBM50114996 3-(4-Chloro-3-methyl-phenyl)-4-(2,6-difluoro-phenyl)-3H-thiazol-(2E)-ylideneamine::CHEMBL301094

SMILES Cc1cc(ccc1Cl)-n1c(csc1=N)-c1c(F)cccc1F

InChI Key InChIKey=XOZRMOCCYGQSFS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114996   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114996(3-(4-Chloro-3-methyl-phenyl)-4-(2,6-difluoro-pheny...)
Affinity DataKi:  48nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114996(3-(4-Chloro-3-methyl-phenyl)-4-(2,6-difluoro-pheny...)
Affinity DataKi:  48nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114996(3-(4-Chloro-3-methyl-phenyl)-4-(2,6-difluoro-pheny...)
Affinity DataKi:  86nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114996(3-(4-Chloro-3-methyl-phenyl)-4-(2,6-difluoro-pheny...)
Affinity DataKi:  433nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed