BDBM50115644 (+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON

SMILES CN1CCN2C(C1)c1ccccc1Cc1cccnc21

InChI Key InChIKey=RONZAEMNMFQXRA-UHFFFAOYSA-N

Data  56 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115644   

TargetTransporter(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi:  1.64E+3nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat Norepinephrine transpoterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataIC50:  260nMAssay Description:The binding affinity of the compound at the Norepinephrin transpoter reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed